导读
对于大型结直肠肿瘤，内镜黏膜下剥离术（ESD）的主要目的就是整块切除病变且不造成穿孔，所以预测结直肠肿瘤ESD的整块切除失败或穿孔风险对于选择合适的治疗策略至关重要。今天与大家分享一项来自日本静冈癌症中心KenichiroImai发表的研究摘要。
ARisk-PredictionModelforEnBlocResectionFailureorPerforationDuringEndoscopicSubmucosalDissectionofColorectalNeoplasms
结直肠肿瘤内镜黏膜下剥离术中整块切除失败或穿孔的风险预测模型
Objectives目的
Technicaldifficultiesincolorectalendoscopicsubmucosaldissections(ESD)resultinenblocresectionfailureorperforation.ThisstudyaimedtodevelopandvalidateariskscoreforpredictingenblocresectionfailureorperforationinESDofcolorectalneoplasms.
结直肠内镜黏膜下剥离术（ESD）存在一定的技术难度，可能会导致整块切除失败或穿孔。本研究旨在开发和验证用于预测结直肠肿瘤整块切除失败或穿孔的风险评分。
Methods方法
Thissingle-centerobservationalstudyincludedcolorectalneoplasmstreatedwithESDinaJapanesetertiarycancercenter.Withaderivationset(n=),weperformedmultiplelogisticregressiontoidentifysignificantriskfactorsforenblocresectionfailureorperforation.Basedonoddsratios,wedevelopedariskscore,rangingfrom0to10:0-1lowrisk(LR);2-4moderaterisk(MR);and5-10highrisk(HR).Anindependentvalidationset
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